ConclusionsĬonsuming a Mediterranean diet before BC diagnosis may improve long-term prognosis, particularly after menopause and in cases of metastatic breast cancer. This result sustained when restricted to postmenopausal women and was stronger among metastatic BC cases (HR 3-unit 0.81, 95% CI: 0.72–0.91). With no statistically significant departures from linearity, on a continuous scale, a 3-unit increase in the arMED score was associated with an 8% reduced risk of overall mortality (HR 3-unit 0.92, 95% CI: 0.87–0.97). High compared to medium adherence to arMED showed a non-statistically significant association (HR 0.94 95% CI 0.84–1.05). Among all BC survivors, low compared to medium adherence to arMED score was associated with a 13% higher risk of all-cause mortality (HR 1.13, 95%CI 1.01–1.26). ResultsĪfter a mean follow-up of 8.6 years from diagnosis, 2340 women died, including 1475 from breast cancer. Multivariable Cox proportional hazards models were used to analyze the association between the arMED score and overall mortality, and Fine-Gray competing risks models were applied for BC-specific mortality. The degree of adherence to arMED was classified as low (score 0–5), medium (score 6–8), and high (score 9–16). Adherence to Mediterranean diet was estimated through the adapted relative Mediterranean diet (arMED), a 16-point score that includes 8 key components of the Mediterranean diet and excludes alcohol. MethodsĪ total of 13,270 incident breast cancer cases were identified from an initial sample of 318,686 women in 9 countries from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality. The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. Inmaculada Aguilera-Buenosvinos 24, 28, 30,īMC Medicine volume 21, Article number: 225 ( 2023).Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |